Predicting pediatric cardiac arrest outcomes using early quantitative EEG
Benedetti GM, Pardo AC, Nelson Sanchez-Pinto L, Straley M, Wainwright MS, Kurz JE, Press CA
Resuscitation (2025) · DOI → · PubMed
Cardiac ArrestqEEGMachine Learning
Mark Wainwright, MD, PhD
Neurology, University of Washington / Seattle Children's
Seattle, WA, USA
About
Division Chief of Neurology and Director of the Neurocritical Care Program at Seattle Children's Hospital and Professor of Neurology at the University of Washington. His research focuses on brain monitoring and recovery after pediatric cardiac arrest, stroke, and status epilepticus.
Research Interests
Pediatric Neurocritical CareCardiac ArrestRefractory Status EpilepticusStrokeTraumatic Brain InjuryNon-invasive Neuromonitoring
Publications(28)
Lack of association of first and second-line medication dosing and progression to refractory status epilepticus in children
Barcia Aguilar C, Amengual-Gual M, Brenton JN, Chapman KE, Clark J, Gaillard WD, Goldstein JL, Goodkin HP, Kahoud R, Lai YC, Mikati MA, Morgan LA, Payne ET, Press CA, Reece L, Sands TT, Sannagowdara K, Sheehan T, Shellhaas RA, Tasker RC, Wainwright MS, Zhang B, Loddenkemper T
Seizure (2024) · DOI → · PubMed
Status EpilepticusPharmacology
Exploring pathways leading to drug-resistant epilepsy for patients with cryptogenic new onset refractory status epilepticus
Hanin A, Marois C, Guillemaud M, Chavez M, Cosme L, Hayatou Z, Besnard A, Goudard G, Masson V, Cousyn L, Cheval M, Denis JA, Alkouri R, Lamari F, Bisulli F, Eschbach K, Farias-Moeller R, Gaspard N, Gerard EE, Giovannini G, Gofton T, Gopaul MT, Kellogg M, Meletti S, Muccioli L, Pasini E, Taraschenko O, Torcida N, Wainwright MS, Yoo JY, Wong N, Bonnefont-Rousselot D, Demeret S, Hirsch LJ, Navarro V
Epilepsia (2026) · DOI → · PubMed
NORSE/FIRESEpilepsyStatus Epilepticus
Severe Pediatric Neurological Manifestations With SARS-CoV-2 or MIS-C Hospitalization and 1-Year Outcomes
Francoeur C, Alcamo AM, Robertson CL, Wainwright MS, Appavu B
JAMA Netw Open (2024) · PubMed
COVID-19Neurocritical Care
A Survey of Neuromonitoring Practices in North American PICUs
Kirschen MP, LaRovere K, Balakrishnan B, Erklauer J, Francoeur C, Ganesan SL, Jayakar A, Lovett M, Luchette M, Press CA, Wolf M, Ferrazzano P, Wainwright MS, Appavu B
Pediatr Neurol (2022) · PubMed
NeuromonitoringSurveyNeurocritical Care
Preventable Pediatric Stroke via Vaccination?
Press CA, Wainwright MS
Pediatr Neurol Briefs (2015) · DOI → · PubMed
Stroke
Spectral Electroencephalogram Analysis for the Evaluation of Encephalopathy Grade in Children With Acute Liver Failure
Press CA, Morgan L, Mills M, Stack CV, Goldstein JL, Alonso EM, Wainwright MS
Pediatr Crit Care Med (2017) · DOI → · PubMed
qEEGCardiac ArrestNeurocritical Care
Early Presence of Sleep Spindles on Electroencephalography Is Associated With Good Outcome After Pediatric Cardiac Arrest
Ducharme-Crevier L, Press CA, Kurz JE, Mills MG, Goldstein JL, Wainwright MS
Pediatr Crit Care Med (2017) · DOI → · PubMed
EEGCardiac ArrestSleep
The Spectrum of Quantitative EEG Utilization Across North America: A Cross-Sectional Survey
Benedetti GM, Morgan LA, Sansevere AJ, Harrar DB, Guerriero RM, Wainwright MS, LaRovere KL, Kielian A, Ganesan SL, Press CA
Pediatr Neurol (2023) · PubMed
qEEGSurveyNeuromonitoring
The onset of pediatric refractory status epilepticus is not distributed uniformly during the day
Sanchez Fernandez I, Gainza-Lein M, Abend NS, Amengual-Gual M, Anderson A, Arya R, Brenton JN, Carpenter JL, Chapman KE, Clark J, Farias-Moeller R, Davis Gaillard W, Glauser TA, Goldstein J, Goodkin HP, Guerriero RM, Hecox K, Jackson M, Kapur K, Kelley SA, Kossoff EHW, Lai YC, McDonough TL, Mikati MA, Morgan LA, Novotny EJ, Ostendorf AP, Payne ET, Peariso K, Piantino J, Riviello JJ, Sannagowdara K, Stafstrom CE, Tasker RC, Tchapyjnikov D, Topjian AA, Vasquez A, Wainwright MS, Wilfong A, Williams K, Loddenkemper T
Seizure (2019) · DOI → · PubMed
Status Epilepticus
Association of guideline publication and delays to treatment in pediatric status epilepticus
Sánchez Fernández I, Abend NS, Amengual-Gual M, Anderson A, Arya R, Barcia Aguilar C, Brenton JN, Carpenter JL, Chapman KE, Clark J, Farias-Moeller R, Gaillard WD, Gaínza-Lein M, Glauser T, Goldstein J, Goodkin HP, Guerriero RM, Lai YC, McDonough T, Mikati MA, Morgan LA, Novotny E, Payne E, Peariso K, Piantino J, Ostendorf A, Sands TT, Sannagowdara K, Tasker RC, Tchapyjnikov D, Topjian AA, Vasquez A, Wainwright MS, Wilfong A, Williams K, Loddenkemper T
Neurology (2020) · DOI → · PubMed
Status EpilepticusPharmacologyOutcomes
First-line medication dosing in pediatric refractory status epilepticus
Vasquez A, Gaínza-Lein M, Abend NS, Amengual-Gual M, Anderson A, Arya R, Brenton JN, Carpenter JL, Chapman K, Clark J, Farias-Moeller R, Gaillard WD, Glauser T, Goldstein JL, Goodkin HP, Guerriero RM, Kapur K, Lai YC, McDonough TL, Mikati MA, Morgan LA, Novotny EJ, Ostendorf AP, Payne ET, Peariso K, Piantino J, Riviello JJ, Sannagowdara K, Tasker RC, Tchapyjnikov D, Topjian A, Wainwright MS, Wilfong A, Williams K, Loddenkemper T
Neurology (2020) · DOI → · PubMed
Status EpilepticusPharmacologyBiomarkers
Time to Treatment in Pediatric Convulsive Refractory Status Epilepticus: The Weekend Effect
Barcia Aguilar C, Amengual-Gual M, Sánchez Fernández I, Abend NS, Anderson A, Appavu B, Arya R, Brenton JN, Carpenter JL, Chapman KE, Clark J, Farias-Moeller R, Gaillard WD, Gaínza-Lein M, Glauser T, Goldstein JL, Goodkin HP, Guerriero RM, Huh L, Lai YC, McDonough TL, Mikati MA, Morgan LA, Novotny EJ, Ostendorf A, Payne ET, Peariso K, Piantino J, Riviello J, Sannagowdara K, Sheehan T, Sands TT, Tasker RC, Tchapyjnikov D, Topjian AA, Vasquez A, Wainwright MS, Wilfong AA, Williams K, Loddenkemper T
Pediatr Neurol (2021) · DOI → · PubMed
Status EpilepticusPharmacologyOutcomes
Super-Refractory Status Epilepticus in Children: A Retrospective Cohort Study
Vasquez A, Farias-Moeller R, Sánchez-Fernández I, Abend NS, Amengual-Gual M, Anderson A, Arya R, Brenton JN, Carpenter JL, Chapman K, Clark J, Gaillard WD, Glauser T, Goldstein JL, Goodkin HP, Guerriero RM, Lai YC, McDonough TL, Mikati MA, Morgan LA, Novotny EJ, Ostendorf AP, Payne ET, Peariso K, Piantino J, Riviello JJ, Sands TT, Sannagowdara K, Tasker RC, Tchapyjnikov D, Topjian A, Wainwright MS, Wilfong A, Williams K, Loddenkemper T
Pediatr Crit Care Med (2021) · DOI → · PubMed
Status EpilepticusPharmacologyOutcomes
Factors associated with long-term outcomes in pediatric refractory status epilepticus
Gaínza-Lein M, Barcia Aguilar C, Piantino J, Chapman KE, Sánchez Fernández I, Amengual-Gual M, Anderson A, Appavu B, Arya R, Brenton JN, Carpenter JL, Clark J, Farias-Moeller R, Gaillard WD, Glauser TA, Goldstein JL, Goodkin HP, Huh L, Kahoud R, Kapur K, Lai YC, McDonough TL, Mikati MA, Morgan LA, Nayak A, Novotny E, Ostendorf AP, Payne ET, Peariso K, Reece L, Riviello J, Sannagowdara K, Sands TT, Sheehan T, Tasker RC, Tchapyjnikov D, Vasquez A, Wainwright MS, Wilfong A, Williams K, Zhang B, Loddenkemper T
Epilepsia (2021) · DOI → · PubMed
Status EpilepticusBiomarkersOutcomes
Benzodiazepine administration patterns before escalation to second-line medications in pediatric refractory convulsive status epilepticus
Sheehan T, Amengual-Gual M, Vasquez A, Abend NS, Anderson A, Appavu B, Arya R, Barcia Aguilar C, Brenton JN, Carpenter JL, Chapman KE, Clark J, Farias-Moeller R, Gaillard WD, Gaínza-Lein M, Glauser TA, Goldstein JL, Goodkin HP, Guerriero RM, Huh L, Jackson M, Kapur K, Kahoud R, Lai YC, McDonough TL, Mikati MA, Morgan LA, Novotny EJ, Ostendorf AP, Payne ET, Peariso K, Piantino J, Reece L, Riviello JJ, Sands TT, Sannagowdara K, Shellhaas R, Smith G, Tasker RC, Tchapyjnikov D, Topjian AA, Wainwright MS, Wilfong A, Williams K, Zhang B, Loddenkemper T
Epilepsia (2021) · DOI → · PubMed
Status EpilepticusPharmacologyOutcomes
Pediatric Critical Care Neurologists in the United States and Canada: A Survey of Clinical Practice Experience
Farias-Moeller R, Jayakar A, Guerriero RM, Carpenter JL, Wainwright MS, Harrar DB
J Child Neurol (2022) · DOI → · PubMed
Neurocritical CareSurveyEducation
A Virtual Community of Practice: An International Educational Series in Pediatric Neurocritical Care
Erklauer JC, Thomas AX, Hong SJ, Appavu BL, Carpenter JL, Chiriboga-Salazar NR, Ferrazzano PA, Goldstein Z, Griffith JL, Guilliams KP, Kirschen MP, Lidsky K, Lovett ME, McLaughlin B, Munoz Pareja JC, Murphy S, O'Donnell W, Riviello JJ, Schober ME, Topjian AA, Wainwright MS, Simon DW
Children (Basel) (2022) · DOI → · PubMed
Neurocritical CareEducation
Safety of intravenous lacosamide in hospitalized children and neonates
Fong SL, Utidjian L, Kaur M, Abend NS, Wainwright MS, Grande KM, Foskett N, Roebling R, Guerriero RM, Jain B, Rao S, Stoltenberg M, Williams P, Yuen N, Dickinson K, McDonald J, Maltenfort M, Forrest CB
Epilepsia (2023) · DOI → · PubMed
Cardiac ArrestNeonatalSeizuresPharmacology
Early Clinical Variables Associated With Refractory Convulsive Status Epilepticus in Children
Peariso K, Arya R, Glauser T, Abend NS, Barcia Aguilar C, Amengual-Gual M, Anderson A, Appavu BL, Brenton JN, Carpenter J, Chapman KE, Clark J, Gaillard WD, Gaínza-Lein M, Goldstein J, Goodkin H, Grinspan Z, Guerriero RM, Horn PS, Huh L, Kahoud R, Kelley SA, Kossoff EH, Kapur K, Lai YC, Marquis BO, McDonough T, Mikati MA, Morgan L, Novotny E, Ostendorf AP, Payne ET, Piantino J, Riviello J, Sands T, Stafstrom CE, Tasker RC, Tchapyjnikov D, Vasquez A, Wainwright MS, Wilfong A, Williams K, Loddenkemper T
Neurology (2023) · DOI → · PubMed
Status EpilepticusPharmacologyBiomarkers
A Survey of Pediatric Neurocritical Care Fellowship Training in North America
Hong SJ, Wainwright MS, Abend NS, Appavu BL, Francoeur C, Erklauer JC, Guerguerian AM, Guerriero RM, Guilliams KP, Lee-Eng J, Loeb J, Lovett ME, Murphy SA, Pardo AC, Pineda JA, Ruzas CM, Topjian AA
Pediatr Neurol (2023) · DOI → · PubMed
Neurocritical CareEEGSurveyEducation
Pediatric status epilepticus management by Emergency Medical Services (the pSERG cohort)
Amengual-Gual M, Sánchez Fernández I, Vasquez A, Abend NS, Anderson A, Arya R, Barcia Aguilar C, Brenton JN, Carpenter JL, Chapman KE, Clark J, Farias-Moeller R, Gaillard WD, Glauser TA, Goldstein JL, Goodkin HP, Lai YC, Mikati MA, Morgan LA, Novotny EJ, Ostendorf AP, Payne ET, Peariso K, Piantino J, Reece L, Riviello JJ, Sannagowdara K, Sheehan T, Tasker RC, Tchapyjnikov D, Topjian AA, Wainwright MS, Wilfong A, Williams K, Loddenkemper T
Seizure (2023) · DOI → · PubMed
Status EpilepticusPharmacologyOutcomes
Time to treatment in pediatric patients with repeated episodes of status epilepticus
Gettings JV, Fernández IS, Anderson A, Brenton JN, Can A, Clark J, Moeller RF, Goodkin HP, Lai YC, Mikati MA, Morgan LA, Novotny E, Ostendorf AP, Piantino J, Riviello JJ, Sannagowdara K, Tasker RC, Tchapyjnikov D, Wainwright MS, Wilfong A, Williams K, Zhang B, Loddenkemper T, Gaínza-Lein M
BMC Neurol (2025) · DOI → · PubMed
Status EpilepticusEducationPharmacologyBiomarkers
A Virtual Community of Practice: An International Educational Series in Pediatric Neurocritical Care
Erklauer JC, Thomas AX, Hong SJ, Appavu BL, Carpenter JL, Chiriboga-Salazar NR, Ferrazzano PA, Goldstein Z, Griffith JL, Guilliams KP, Kirschen MP, Lidsky K, Lovett ME, McLaughlin B, Munoz Pareja JC, Murphy S, O'Donnell W, Riviello JJ, Schober ME, Topjian AA, Wainwright MS, Simon DW, Pediatric Neurocritical Care Research Group
Children (2022) · DOI → · PubMed
EducationNeurocritical Care
Practice Standards for the Use of Multimodality Neuromonitoring: A Delphi Consensus Process.
Foreman B, Kapinos G, Wainwright MS, Ngwenya LB, O'Phelan KH, LaRovere KL, Kirschen MP, Appavu B, Lazaridis C, Alkhachroum A, Maciel CB, Amorim E, Chang JJ, Gilmore EJ, Rosenthal ES, Park S
Crit Care Med (2023) · DOI → · PubMed
Neurocritical CareTBINeuromonitoringEducation
Post-discharge outcomes of hospitalized children diagnosed with acute SARS-CoV-2 or MIS-C.
Fink EL, Alcamo AM, Lovett M, Hartman M, Williams C, Garcia A, Rasmussen L, Pal R, Drury K, MackDiaz E, Ferrazzano PA, Dervan L, Appavu B, Snooks K, Stulce C, Rubin P, Pate B, Toney N, Robertson CL, Wainwright MS, Roa JD, Schober ME, Slomine BS
Front Pediatr (2024) · DOI → · PubMed
Neurocritical CareCOVID-19Outcomes
Corrigendum: Post-discharge outcomes of hospitalized children diagnosed with acute SARS-CoV-2 or MIS-C.
Fink EL, Alcamo AM, Lovett M, Hartman M, Williams C, Garcia A, Rasmussen L, Pal R, Drury K, MackDiaz E, Ferrazzano PA, Dervan L, Appavu B, Snooks K, Stulce C, Rubin P, Pate B, Toney N, Robertson CL, Wainwright MS, Roa JD, Schober ME, Slomine BS
Front Pediatr (2024) · DOI → · PubMed
COVID-19Outcomes
Prevalence and Risk Factors of Neurologic Manifestations in Hospitalized Children Diagnosed with Acute SARS-CoV-2 or MIS-C.
Fink EL, Robertson CL, Wainwright MS, Roa JD, Lovett ME, Stulce C, Yacoub M, Potera RM, Zivick E, Holloway A, Nagpal A, Wellnitz K, Czech T, Even KM, Brunow de Carvalho W, Rodriguez IS, Schwartz SP, Walker TC, Campos-Mino S, Dervan LA, Geneslaw AS, Sewell TB, Pryce P, Silver WG, Lin JE, Vargas WS, Topjian A, Alcamo AM, McGuire JL, Dominguez Rojas JA, Munoz JT, Hong SJ, Muller WJ, Doerfler M, Williams CN, Drury K, Bhagat D, Nelson A, Price D, Dapul H, Santos L, Kahoud R, Francoeur C, Appavu B, Guilliams KP, Agner SC, Walson KH, Rasmussen L, Janas A, Ferrazzano P, Farias-Moeller R, Snooks KC, Chang CH, Yun J, Schober ME
Pediatr Neurol (2021) · DOI → · PubMed
COVID-19
Conference Abstracts(8)
Early Non-Dichotomous Quantitative EEG Variables Predict Long-Term Outcomes After Pediatric Cardiac Arrest
Benedetti GM, Straley M, Pardo AC, Sanchez-Pinto LN, Wainwright MS, Kurz JE, Press CA
American Epilepsy Society Annual Meeting (2022) · poster
Cardiac ArrestEEGEpilepsyOutcomesqEEG
Predictive Value of Quantitative EEG 24-Hours After Pediatric Cardiac Arrest
Benedetti GM, Straley M, Pardo AC, Sanchez-Pinto LN, Wainwright MS, Kurz JE, Press CA
Neurocritical Care Society Annual Meeting (2022) · oral
Cardiac ArrestEEGNeurocritical CareOutcomesqEEG
Trends in Quantitative EEG Use in Pediatric Critical Care Across North America
Benedetti GM, Morgan LA, Sansevere AJ, Harrar DB, Guerriero RM, Wainwright MS, LaRovere KL, Kielian A, Lalgudi Ganesan S, Press CA
Child Neurology Society Annual Meeting (2022) · poster
EEGNeurocritical CareqEEG
Heart Rate Variability and EEG Characteristics in Children with CAR T-Associated Neurotoxicity
Dervan LA, Doud A, Di Gennaro JL, Benedetti GM, Morgan LA, Amlie-Lefond C, Watson RS, Wainwright M
Society of Critical Care Medicine Annual Meeting (2022) · poster
EEGNeurocritical Care
Neuromonitoring Practice is Highly Variable in Pediatric Extracorporeal Membrane Oxygenation
Ruzas CM, Benedetti GM, Kurz J, Press CA, Kim J, Daniels Z, Smith C, Wainwright MS
Neurocritical Care Society Annual Meeting (2021) · poster
ECMO/ECLSNeurocritical CareNeuromonitoring
Early Quantitative Electroencephalogram Measurements Correlate with Outcome in Pediatric Cardiac Arrest
Benedetti GM, Wainwright MS, Din F, Kurz JE
Child Neurology Society Annual Meeting (2018) · oral
Cardiac ArrestEEGOutcomesqEEG
Variation in Treatment and Outcomes of Children With Acute Disseminated Encephalomyelitis
Press CA, Kirschen M, LaRovere K, Risen S, Guilliams K, Chung M, Griffith J, Erklauer J, Peariso K, Ducharme-Crevier L, Shah S, Hall M, Wainwright M
American Academy of Neurology Annual Meeting (2018) · poster
OutcomesPharmacology
Use of PHIS Database for Outcomes Studies: A Proposed PNCRG Workgroup
Press CA, Wainwright MS
Pediatric Neurocritical Care Research Group (2016) · invited
Neurocritical CareOutcomes