Cecil Hahn, MD

Senior Scientific Advisor

Neurology, The Hospital for Sick Children

Toronto, ON, Canada

About

Senior Scientific Advisor to PedQuEST.

Research Interests

Neonatal EEGPediatric Neurocritical CareClinical Neurophysiology

Publications(33)

Intrathecal Dexamethasone as a FIRES Extinguisher: A 12-Patient Clinical Experience with Usage of Intrathecal Dexamethasone for Febrile Infection-Related Epilepsy Syndrome

Farias-Moeller R, Hanin A, Ahsan S, Brooks J, Caganap SD, Czeisler B, Cheuret E, Cocuzzo B, Hahn CD, Kyureghyan H, Marcoux MO, Mohamed R, Park C, Stern Zimmer M, Barun V, Lai YC, Hirsch LJ

Neurocrit Care (2025) · PubMed

NORSE/FIRESStatus EpilepticusPharmacology

Sex Disparities in the Clinical Management and Outcomes of Critically Ill Adults Undergoing Electroencephalography Monitoring

Urbano V, Alvarez V, Schindler K, Ruegg S, Hahn CD, Beuchat I, Benghanem S, Novy J, Rossetti AO

Crit Care Med (2026) · DOI → · PubMed

EEGNeurocritical Care

The brain in pediatric critical care: unique aspects of assessment, monitoring, investigations, and follow-up

Brown KL, Agrawal S, Kirschen MP, Traube C, Topjian A, Pressler R, Hahn CD, Scholefield BR, Kanthimathinathan HK, Hoskote A, D'Arco F, Bembea M, Manning JC, Hunfeld M, Buysse C, Tasker RC

Intensive Care Med (2022) · DOI → · PubMed

Neurocritical CareNeuromonitoringReview

Choosing wisely: who really benefits from critical care EEG monitoring?

Hahn CD, Rossetti AO

Intensive Care Med (2025) · PubMed

EEGNeurocritical Care

Conventional and quantitative EEG in status epilepticus

Sansevere AJ, Hahn CD, Abend NS

Seizure (2018) · DOI → · PubMed

qEEGStatus EpilepticusReview

Hyperglycemia and Glucose Variability Are Associated with Worse Brain Function and Seizures in Neonatal Encephalopathy: A Prospective Cohort Study

Pinchefsky EF, Hahn CD, Kamino D, Chau V, Brant R, Moore AM, Tam EWY

J Pediatr (2019) · DOI → · PubMed

EEGNeonatalSeizuresNeurocritical Care

Electrographic seizure burden and outcomes following pediatric status epilepticus

Lalgudi Ganesan S, Hahn CD

Epilepsy Behav (2019) · DOI → · PubMed

Status EpilepticusEEGReviewOutcomes

Neonatal seizures: Case definition & guidelines for data collection, analysis, and presentation of immunization safety data

Pellegrin S, Munoz FM, Padula M, Heath PT, Meller L, Top K, Wilmshurst J, Wiznitzer M, Das MK, Hahn CD, Kucuku M, Oleske J, Vinayan KP, Yozawitz E, Aneja S, Bhat N, Boylan G, Sesay S, Shrestha A, Soul JS, Tagbo B, Joshi J, Soe A, Maltezou HC, Gidudu J, Kochhar S, Pressler RM

Vaccine (2019) · DOI → · PubMed

NeonatalSeizuresReview

Seizure Detection Algorithms in Critically Ill Children: A Comparative Evaluation

Din F, Lalgudi Ganesan S, Akiyama T, Stewart CP, Ochi A, Otsubo H, Go C, Hahn CD

Crit Care Med (2020) · DOI → · PubMed

EEGSeizures

Epilepsy and Electroencephalographic Abnormalities in SATB2-Associated Syndrome

Lewis H, Samanta D, Örsell JL, Bosanko KA, Rowell A, Jones M, Dale RC, Taravath S, Hahn CD, Krishnakumar D, Chagnon S, Keller S, Hagebeuk E, Pathak S, Bebin EM, Arndt DH, Alexander JJ, Mainali G, Coppola G, Maclean J, Sparagana S, McNamara N, Smith DM, Raggio V, Cruz M, Fernández-Jaén A, Kava MP, Emrick L, Fish JL, Vanderver A, Helman G, Pierson TM, Zarate YA

Pediatr Neurol (2020) · DOI → · PubMed

EEGSeizuresSurveyNeurocritical CareEpilepsy

Educational initiatives and implementation of electroencephalography into the acute care environment: a protocol of a systematic review

Taran S, Ahmed W, Bui E, Prisco L, Hahn CD, McCredie VA

Syst Rev (2020) · DOI → · PubMed

Status EpilepticusEEGEducationOutcomes

American Clinical Neurophysiology Society's Standardized Critical Care EEG Terminology: 2021 Version

Hirsch LJ, Fong MWK, Leitinger M, LaRoche SM, Beniczky S, Abend NS, Lee JW, Wusthoff CJ, Hahn CD, Westover MB, Gerard EE, Herman ST, Haider HA, Osman G, Rodriguez-Ruiz A, Maciel CB, Gilmore EJ, Fernandez A, Rosenthal ES, Claassen J, Husain AM, Yoo JY, So EL, Kaplan PW, Nuwer MR, van Putten M, Sutter R, Drislane FW, Trinka E, Gaspard N

J Clin Neurophysiol (2021) · DOI → · PubMed

EEG

Emergency management of the paediatric patient with convulsive status epilepticus

McKenzie KC, Hahn CD, Friedman JN

Paediatr Child Health (2021) · DOI → · PubMed

Status EpilepticusReviewPharmacology

Prevalence, Risk Factors, and Impact of Preoperative Seizures in Neonates With Congenital Heart Disease

Pittet MP, Marini D, Ly L, Au-Young SH, Chau V, Seed M, Miller SP, Hahn CD

J Clin Neurophysiol (2021) · DOI → · PubMed

EEGNeonatalSeizuresOutcomes

Educational initiatives for electroencephalography in the critical care setting: a systematic review and meta-analysis

Taran S, Ahmed W, Pinto R, Bui E, Prisco L, Hahn CD, Englesakis M, McCredie VA

Can J Anaesth (2021) · DOI → · PubMed

EEGSeizuresReviewEducation

Alterations in coordinated EEG activity precede the development of seizures in comatose children

Vakorin VA, Nita DA, Payne ET, McBain KL, Frndova H, Go C, Ribary U, Abend NS, Gallentine WB, Nash KB, Hutchison JS, Parshuram CS, Snead OC, van Straaten IECW, Stam CJ, Doesburg SM, Hahn CD

Clin Neurophysiol (2021) · DOI → · PubMed

EEGSeizures

Spectrograms for Seizure Detection in Critically Ill Children

Lalgudi Ganesan S, Hahn CD

J Clin Neurophysiol (2022) · DOI → · PubMed

qEEGSeizuresOutcomes

Why monitor the neonatal brain-that is the important question

Vanhatalo S, Stevenson NJ, Pressler RM, Abend NS, Auvin S, Brigo F, Cilio MR, Hahn CD, Hartmann H, Hellström-Westas L, Inder TE, Moshé SL, Nunes ML, Shellhaas RA, Vinayan KP, de Vries LS, Wilmshurst JM, Yozawitz E, Boylan GB

Pediatr Res (2022) · DOI → · PubMed

Neurocritical CareNeuromonitoringEEGNeonatalSeizures

A phase 2, randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of soticlestat as adjunctive therapy in pediatric patients with Dravet syndrome or Lennox-Gastaut syndrome (ELEKTRA)

Hahn CD, Jiang Y, Villanueva V, Zolnowska M, Arkilo D, Hsiao S, Asgharnejad M, Dlugos D

Epilepsia (2022) · DOI → · PubMed

SeizuresClinical TrialPharmacology

Machine learning to support triage of children at risk for epileptic seizures in the pediatric intensive care unit

Azriel R, Hahn CD, De Cooman T, Van Huffel S, Payne ET, McBain KL, Eytan D, Behar JA

Physiol Meas (2022) · DOI → · PubMed

EEGSeizuresMachine Learning

Brain network properties of clinical versus subclinical seizures among critically ill children

Koster LK, Zamyadi R, Yan L, Payne ET, McBain KL, Dunkley BT, Hahn CD

Clin Neurophysiol (2023) · DOI → · PubMed

EEGSeizuresOutcomes

Seizure Burden and Neurologic Outcomes After Neonatal Encephalopathy

Alharbi HM, Pinchefsky EF, Tran MA, Salazar Cerda CI, Parokaran Varghese J, Kamino D, Widjaja E, Mamak E, Ly L, Nevalainen P, Hahn CD, Tam EWY

Neurology (2023) · DOI → · PubMed

EEGNeonatalSeizuresPharmacology

Automated Interpretation of Clinical Electroencephalograms Using Artificial Intelligence

Tveit J, Aurlien H, Plis S, Calhoun VD, Tatum WO, Schomer DL, Arntsen V, Cox F, Fahoum F, Gallentine WB, Gardella E, Hahn CD, Husain AM, Kessler S, Kural MA, Nascimento FA, Tankisi H, Ulvin LB, Wennberg R, Beniczky S

JAMA Neurol (2023) · DOI → · PubMed

EEGMachine LearningEpilepsy

The truth Hertz-synchronization of electroencephalogram signals with physiological waveforms recorded in an intensive care unit

Goodwin AJ, Dixon W, Mazwi M, Hahn CD, Meir T, Goodfellow SD, Kazazian V, Greer RW, McEwan A, Laussen PC, Eytan D

Physiol Meas (2023) · DOI → · PubMed

EEG

Treatment of seizures in the neonate: Guidelines and consensus-based recommendations-Special report from the ILAE Task Force on Neonatal Seizures

Pressler RM, Abend NS, Auvin S, Boylan G, Brigo F, Cilio MR, De Vries LS, Elia M, Espeche A, Hahn CD, Inder T, Jette N, Kakooza-Mwesige A, Mader S, Mizrahi EM, Moshé SL, Nagarajan L, Noyman I, Nunes ML, Samia P, Shany E, Shellhaas RA, Subota A, Triki CC, Tsuchida T, Vinayan KP, Wilmshurst JM, Yozawitz EG, Hartmann H

Epilepsia (2023) · DOI → · PubMed

EEGNeonatalSeizuresStrokeReviewPharmacology

Automated assessment of EEG background for neurodevelopmental prediction in neonatal encephalopathy

Lagacé M, Montazeri S, Kamino D, Mamak E, Ly LG, Hahn CD, Chau V, Vanhatalo S, Tam EWY

Ann Clin Transl Neurol (2024) · DOI → · PubMed

EEGNeonatalMachine LearningBiomarkers

The American Clinical Neurophysiology Society Guideline on Indications for Continuous Electroencephalography Monitoring in Neonates

Wusthoff CJ, Numis AL, Pressler RM, Chu CJ, Massey S, Clancy RR, Nguyen S, Hahn CD, Scher MS, Pilon B, King DT, Wong HN, Tsuchida TN, Riviello JJ, Shellhaas RA

J Clin Neurophysiol (2024) · DOI → · PubMed

EEGNeonatalSeizuresOutcomes

Comparison of lacosamide, levetiracetam, and valproate as second-line therapy in adult status epilepticus: Analysis of a large cohort

Hahn CD, Novy J, Rossetti AO

Epilepsia (2025) · DOI → · PubMed

Status EpilepticusPharmacologyOutcomes

Midazolam infusions for therapeutic management of pediatric refractory status epilepticus: a systematic review

Johnson KT, AlZadjali A, Al Nasseri D, Cunningham J, Shoya K, Hahn CD, Basmaji J, McKinnon NK

Front Pediatr (2025) · DOI → · PubMed

Status EpilepticusReview

Neurophysiological changes associated with dysglycemia in term neonates with neonatal encephalopathy

Parokaran Varghese J, Pinchefsky EF, Montazeri S, Kamino D, Hahn CD, Vanhatalo S, Tam EW

Clin Neurophysiol (2025) · DOI → · PubMed

EEGNeonatalNeurocritical Care

Survey of Pediatric ICU EEG Monitoring-Reassessment After a Decade.

Fung FW, Carpenter JL, Chapman KE, Gallentine W, Giza CC, Goldstein JL, Hahn CD, Loddenkemper T, Matsumoto JH, Press CA, Riviello JJ, Abend NS

J Clin Neurophysiol (2023) · DOI → · PubMed

EEGSeizuresEpilepsyStatus EpilepticusNeurocritical Care

Common Data Elements for Disorders of Consciousness: Recommendations from the Working Group on Biospecimens and Biomarkers.

Shah VA, Hinson HE, Reznik ME, Hahn CD, Alexander S, Elmer J, Chou SH

Neurocrit Care (2023) · DOI → · PubMed

CerebrovascularTBIBiomarkersOutcomesDisorders of Consciousness

Correction: Common Data Elements for Disorders of Consciousness: Recommendations from the Working Group on Biospecimens and Biomarkers.

Shah VA, Hinson HE, Reznik ME, Hahn CD, Alexander S, Elmer J, Chou SH

Neurocrit Care (2025) · DOI → · PubMed

BiomarkersDisorders of Consciousness

Conference Abstracts(1)

Survey of Pediatric ICU EEG Monitoring - Reassessment After a Decade

Fung FW, Carpenter JL, Chapman KE, Gallentine W, Giza CC, Goldstein JL, Hahn CD, Loddenkemper T, Matsumoto JH, Press CA, Riviello JJ Jr, Abend NS

American Clinical Neurophysiology Society Meeting (2023) · poster

EEGNeurocritical CareNeuromonitoring