Status Epilepticus Is Detected Earlier than Seizures on cEEG in Critically Ill Adults.
Rossetti AO, Hahn CD, Novy J, Alvarez V, Schindler K, Rüegg S, Lee JW
Cecil Hahn, MD
Senior Scientific Advisor
Neurology, The Hospital for Sick Children
Toronto, ON, Canada
About
Senior Scientific Advisor to PedQuEST.
Research Interests
Neonatal EEGPediatric Neurocritical CareClinical Neurophysiology
Publications(36)
Sex Disparities in the Clinical Management and Outcomes of Critically Ill Adults Undergoing Electroencephalography Monitoring
Urbano V, Alvarez V, Schindler K, Ruegg S, Hahn CD, Beuchat I, Benghanem S, Novy J, Rossetti AO
Crit Care Med (2026) · DOI → · PubMed
EEGNeurocritical Care
Neurophysiological changes associated with dysglycemia in term neonates with neonatal encephalopathy
Parokaran Varghese J, Pinchefsky EF, Montazeri S, Kamino D, Hahn CD, Vanhatalo S, Tam EW
Clin Neurophysiol (2025) · DOI → · PubMed
EEGNeonatalNeurocritical Care
Midazolam infusions for therapeutic management of pediatric refractory status epilepticus: a systematic review
Johnson KT, AlZadjali A, Al Nasseri D, Cunningham J, Shoya K, Hahn CD, Basmaji J, McKinnon NK
Front Pediatr (2025) · DOI → · PubMed
Status EpilepticusReview
Comparison of lacosamide, levetiracetam, and valproate as second-line therapy in adult status epilepticus: Analysis of a large cohort
Hahn CD, Novy J, Rossetti AO
Epilepsia (2025) · DOI → · PubMed
Status EpilepticusPharmacologyOutcomes
Correction: Common Data Elements for Disorders of Consciousness: Recommendations from the Working Group in the Pediatric Population.
Boerwinkle VL, Appavu B, Cediel EG, Erklaurer J, Lalgudi Ganesan S, Gibbons C, Hahn C, LaRovere KL, Moberg D, Natarajan G, Molteni E, Reuther WR, Slomine BS
Neurocrit Care (2025) · DOI → · PubMed
Disorders of Consciousness
Correction: Common Data Elements for Disorders of Consciousness: Recommendations from the Working Group on Biospecimens and Biomarkers.
Shah VA, Hinson HE, Reznik ME, Hahn CD, Alexander S, Elmer J, Chou SH
Neurocrit Care (2025) · DOI → · PubMed
BiomarkersDisorders of Consciousness
Choosing wisely: who really benefits from critical care EEG monitoring?
Hahn CD, Rossetti AO
Intensive Care Med (2025) · PubMed
EEGNeurocritical Care
Intrathecal Dexamethasone as a FIRES Extinguisher: A 12-Patient Clinical Experience with Usage of Intrathecal Dexamethasone for Febrile Infection-Related Epilepsy Syndrome
Farias-Moeller R, Hanin A, Ahsan S, Brooks J, Caganap SD, Czeisler B, Cheuret E, Cocuzzo B, Hahn CD, Kyureghyan H, Marcoux MO, Mohamed R, Park C, Stern Zimmer M, Barun V, Lai YC, Hirsch LJ
Neurocrit Care (2025) · PubMed
NORSE/FIRESStatus EpilepticusPharmacology
Automated assessment of EEG background for neurodevelopmental prediction in neonatal encephalopathy
Lagacé M, Montazeri S, Kamino D, Mamak E, Ly LG, Hahn CD, Chau V, Vanhatalo S, Tam EWY
Ann Clin Transl Neurol (2024) · DOI → · PubMed
EEGNeonatalMachine LearningBiomarkers
The American Clinical Neurophysiology Society Guideline on Indications for Continuous Electroencephalography Monitoring in Neonates
Wusthoff CJ, Numis AL, Pressler RM, Chu CJ, Massey S, Clancy RR, Nguyen S, Hahn CD, Scher MS, Pilon B, King DT, Wong HN, Tsuchida TN, Riviello JJ, Shellhaas RA
J Clin Neurophysiol (2024) · DOI → · PubMed
EEGNeonatalSeizuresOutcomes
Common Data Elements for Disorders of Consciousness: Recommendations from the Working Group in the Pediatric Population.
Boerwinkle VL, Appavu B, Cediel EG, Erklaurer J, Lalgudi Ganesan S, Gibbons C, Hahn C, LaRovere KL, Moberg D, Natarajan G, Molteni E, Reuther WR, Slomine BS
Neurocrit Care (2023) · DOI → · PubMed
NeonatalNeurocritical CareNeuroimagingBiomarkersOutcomesDisorders of ConsciousnessReliability
Common Data Elements for Disorders of Consciousness: Recommendations from the Working Group on Biospecimens and Biomarkers.
Shah VA, Hinson HE, Reznik ME, Hahn CD, Alexander S, Elmer J, Chou SH
Neurocrit Care (2023) · DOI → · PubMed
CerebrovascularTBIBiomarkersOutcomesDisorders of Consciousness
Treatment of seizures in the neonate: Guidelines and consensus-based recommendations-Special report from the ILAE Task Force on Neonatal Seizures
Pressler RM, Abend NS, Auvin S, Boylan G, Brigo F, Cilio MR, De Vries LS, Elia M, Espeche A, Hahn CD, Inder T, Jette N, Kakooza-Mwesige A, Mader S, Mizrahi EM, Moshé SL, Nagarajan L, Noyman I, Nunes ML, Samia P, Shany E, Shellhaas RA, Subota A, Triki CC, Tsuchida T, Vinayan KP, Wilmshurst JM, Yozawitz EG, Hartmann H
Epilepsia (2023) · DOI → · PubMed
EEGNeonatalSeizuresStrokeReviewPharmacology
Automated Interpretation of Clinical Electroencephalograms Using Artificial Intelligence
Tveit J, Aurlien H, Plis S, Calhoun VD, Tatum WO, Schomer DL, Arntsen V, Cox F, Fahoum F, Gallentine WB, Gardella E, Hahn CD, Husain AM, Kessler S, Kural MA, Nascimento FA, Tankisi H, Ulvin LB, Wennberg R, Beniczky S
JAMA Neurol (2023) · DOI → · PubMed
EEGMachine LearningEpilepsy
The truth Hertz-synchronization of electroencephalogram signals with physiological waveforms recorded in an intensive care unit
Goodwin AJ, Dixon W, Mazwi M, Hahn CD, Meir T, Goodfellow SD, Kazazian V, Greer RW, McEwan A, Laussen PC, Eytan D
Physiol Meas (2023) · DOI → · PubMed
EEG
Seizure Burden and Neurologic Outcomes After Neonatal Encephalopathy
Alharbi HM, Pinchefsky EF, Tran MA, Salazar Cerda CI, Parokaran Varghese J, Kamino D, Widjaja E, Mamak E, Ly L, Nevalainen P, Hahn CD, Tam EWY
Neurology (2023) · DOI → · PubMed
EEGNeonatalSeizuresPharmacology
Survey of Pediatric ICU EEG Monitoring-Reassessment After a Decade.
Fung FW, Carpenter JL, Chapman KE, Gallentine W, Giza CC, Goldstein JL, Hahn CD, Loddenkemper T, Matsumoto JH, Press CA, Riviello JJ, Abend NS
J Clin Neurophysiol (2023) · DOI → · PubMed
EEGSeizuresEpilepsyStatus EpilepticusNeurocritical Care
Brain network properties of clinical versus subclinical seizures among critically ill children
Koster LK, Zamyadi R, Yan L, Payne ET, McBain KL, Dunkley BT, Hahn CD
Clin Neurophysiol (2023) · DOI → · PubMed
EEGSeizuresOutcomes
Machine learning to support triage of children at risk for epileptic seizures in the pediatric intensive care unit
Azriel R, Hahn CD, De Cooman T, Van Huffel S, Payne ET, McBain KL, Eytan D, Behar JA
Physiol Meas (2022) · DOI → · PubMed
EEGSeizuresMachine Learning
A phase 2, randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of soticlestat as adjunctive therapy in pediatric patients with Dravet syndrome or Lennox-Gastaut syndrome (ELEKTRA)
Hahn CD, Jiang Y, Villanueva V, Zolnowska M, Arkilo D, Hsiao S, Asgharnejad M, Dlugos D
Epilepsia (2022) · DOI → · PubMed
SeizuresClinical TrialPharmacology
The brain in pediatric critical care: unique aspects of assessment, monitoring, investigations, and follow-up
Brown KL, Agrawal S, Kirschen MP, Traube C, Topjian A, Pressler R, Hahn CD, Scholefield BR, Kanthimathinathan HK, Hoskote A, D'Arco F, Bembea M, Manning JC, Hunfeld M, Buysse C, Tasker RC
Intensive Care Med (2022) · DOI → · PubMed
Neurocritical CareNeuromonitoringReview
Why monitor the neonatal brain-that is the important question
Vanhatalo S, Stevenson NJ, Pressler RM, Abend NS, Auvin S, Brigo F, Cilio MR, Hahn CD, Hartmann H, Hellström-Westas L, Inder TE, Moshé SL, Nunes ML, Shellhaas RA, Vinayan KP, de Vries LS, Wilmshurst JM, Yozawitz E, Boylan GB
Pediatr Res (2022) · DOI → · PubMed
Neurocritical CareNeuromonitoringEEGNeonatalSeizures
Spectrograms for Seizure Detection in Critically Ill Children
Lalgudi Ganesan S, Hahn CD
J Clin Neurophysiol (2022) · DOI → · PubMed
qEEGSeizuresOutcomes
Alterations in coordinated EEG activity precede the development of seizures in comatose children
Vakorin VA, Nita DA, Payne ET, McBain KL, Frndova H, Go C, Ribary U, Abend NS, Gallentine WB, Nash KB, Hutchison JS, Parshuram CS, Snead OC, van Straaten IECW, Stam CJ, Doesburg SM, Hahn CD
Clin Neurophysiol (2021) · DOI → · PubMed
EEGSeizures
Educational initiatives for electroencephalography in the critical care setting: a systematic review and meta-analysis
Taran S, Ahmed W, Pinto R, Bui E, Prisco L, Hahn CD, Englesakis M, McCredie VA
Can J Anaesth (2021) · DOI → · PubMed
EEGSeizuresReviewEducation
Prevalence, Risk Factors, and Impact of Preoperative Seizures in Neonates With Congenital Heart Disease
Pittet MP, Marini D, Ly L, Au-Young SH, Chau V, Seed M, Miller SP, Hahn CD
J Clin Neurophysiol (2021) · DOI → · PubMed
EEGNeonatalSeizuresOutcomes
American Clinical Neurophysiology Society's Standardized Critical Care EEG Terminology: 2021 Version
Hirsch LJ, Fong MWK, Leitinger M, LaRoche SM, Beniczky S, Abend NS, Lee JW, Wusthoff CJ, Hahn CD, Westover MB, Gerard EE, Herman ST, Haider HA, Osman G, Rodriguez-Ruiz A, Maciel CB, Gilmore EJ, Fernandez A, Rosenthal ES, Claassen J, Husain AM, Yoo JY, So EL, Kaplan PW, Nuwer MR, van Putten M, Sutter R, Drislane FW, Trinka E, Gaspard N
J Clin Neurophysiol (2021) · DOI → · PubMed
EEG
Emergency management of the paediatric patient with convulsive status epilepticus
McKenzie KC, Hahn CD, Friedman JN
Paediatr Child Health (2021) · DOI → · PubMed
Status EpilepticusReviewPharmacology
Educational initiatives and implementation of electroencephalography into the acute care environment: a protocol of a systematic review
Taran S, Ahmed W, Bui E, Prisco L, Hahn CD, McCredie VA
Syst Rev (2020) · DOI → · PubMed
Status EpilepticusEEGEducationOutcomes
Epilepsy and Electroencephalographic Abnormalities in SATB2-Associated Syndrome
Lewis H, Samanta D, Örsell JL, Bosanko KA, Rowell A, Jones M, Dale RC, Taravath S, Hahn CD, Krishnakumar D, Chagnon S, Keller S, Hagebeuk E, Pathak S, Bebin EM, Arndt DH, Alexander JJ, Mainali G, Coppola G, Maclean J, Sparagana S, McNamara N, Smith DM, Raggio V, Cruz M, Fernández-Jaén A, Kava MP, Emrick L, Fish JL, Vanderver A, Helman G, Pierson TM, Zarate YA
Pediatr Neurol (2020) · DOI → · PubMed
EEGSeizuresSurveyNeurocritical CareEpilepsy
Seizure Detection Algorithms in Critically Ill Children: A Comparative Evaluation
Din F, Lalgudi Ganesan S, Akiyama T, Stewart CP, Ochi A, Otsubo H, Go C, Hahn CD
Crit Care Med (2020) · DOI → · PubMed
EEGSeizures
Neonatal seizures: Case definition & guidelines for data collection, analysis, and presentation of immunization safety data
Pellegrin S, Munoz FM, Padula M, Heath PT, Meller L, Top K, Wilmshurst J, Wiznitzer M, Das MK, Hahn CD, Kucuku M, Oleske J, Vinayan KP, Yozawitz E, Aneja S, Bhat N, Boylan G, Sesay S, Shrestha A, Soul JS, Tagbo B, Joshi J, Soe A, Maltezou HC, Gidudu J, Kochhar S, Pressler RM
Vaccine (2019) · DOI → · PubMed
NeonatalSeizuresReview
Electrographic seizure burden and outcomes following pediatric status epilepticus
Lalgudi Ganesan S, Hahn CD
Epilepsy Behav (2019) · DOI → · PubMed
Status EpilepticusEEGReviewOutcomes
Hyperglycemia and Glucose Variability Are Associated with Worse Brain Function and Seizures in Neonatal Encephalopathy: A Prospective Cohort Study
Pinchefsky EF, Hahn CD, Kamino D, Chau V, Brant R, Moore AM, Tam EWY
J Pediatr (2019) · DOI → · PubMed
EEGNeonatalSeizuresNeurocritical Care
Conventional and quantitative EEG in status epilepticus
Sansevere AJ, Hahn CD, Abend NS
Seizure (2018) · DOI → · PubMed
qEEGStatus EpilepticusReview
Conference Abstracts(1)
Survey of Pediatric ICU EEG Monitoring - Reassessment After a Decade
Fung FW, Carpenter JL, Chapman KE, Gallentine W, Giza CC, Goldstein JL, Hahn CD, Loddenkemper T, Matsumoto JH, Press CA, Riviello JJ Jr, Abend NS
American Clinical Neurophysiology Society Meeting (2023) · poster
EEGNeurocritical CareNeuromonitoring