Adam Ostendorf, MD

Division of Neurology, Nationwide Children's Hospital, Nationwide Children's Hospital

Columbus, OH, USA

About

Associate Division Chief of Research and associate professor of Pediatrics at The Ohio State University College of Medicine. Medical director of the epilepsy surgery program at Nationwide Children's Hospital, one of the largest pediatric programs in the U.S.

Research Interests

Status EpilepticusQuality ImprovementPediatric Neurology

Website

Publications(33)

Status epilepticus treatment: multicenter quality improvement

Ostendorf AP, Loddenkemper T, Morgan LA, Appavu B, Farias-Moeller R, Harrar D, Press C, Abend NS, Gaillard WD, Bai S, Eisner M, McHenry L, Kroshus E, Vannatta K, Goodkin HP

Contemp Clin Trials (2025) · PubMed

Status EpilepticusClinical Trial

The onset of pediatric refractory status epilepticus is not distributed uniformly during the day

Sanchez Fernandez I, Gainza-Lein M, Abend NS, Amengual-Gual M, Anderson A, Arya R, Brenton JN, Carpenter JL, Chapman KE, Clark J, Farias-Moeller R, Davis Gaillard W, Glauser TA, Goldstein J, Goodkin HP, Guerriero RM, Hecox K, Jackson M, Kapur K, Kelley SA, Kossoff EHW, Lai YC, McDonough TL, Mikati MA, Morgan LA, Novotny EJ, Ostendorf AP, Payne ET, Peariso K, Piantino J, Riviello JJ, Sannagowdara K, Stafstrom CE, Tasker RC, Tchapyjnikov D, Topjian AA, Vasquez A, Wainwright MS, Wilfong A, Williams K, Loddenkemper T

Seizure (2019) · DOI → · PubMed

Status Epilepticus

First-line medication dosing in pediatric refractory status epilepticus

Vasquez A, Gaínza-Lein M, Abend NS, Amengual-Gual M, Anderson A, Arya R, Brenton JN, Carpenter JL, Chapman K, Clark J, Farias-Moeller R, Gaillard WD, Glauser T, Goldstein JL, Goodkin HP, Guerriero RM, Kapur K, Lai YC, McDonough TL, Mikati MA, Morgan LA, Novotny EJ, Ostendorf AP, Payne ET, Peariso K, Piantino J, Riviello JJ, Sannagowdara K, Tasker RC, Tchapyjnikov D, Topjian A, Wainwright MS, Wilfong A, Williams K, Loddenkemper T

Neurology (2020) · DOI → · PubMed

Status EpilepticusPharmacologyBiomarkers

Super-Refractory Status Epilepticus in Children: A Retrospective Cohort Study

Vasquez A, Farias-Moeller R, Sánchez-Fernández I, Abend NS, Amengual-Gual M, Anderson A, Arya R, Brenton JN, Carpenter JL, Chapman K, Clark J, Gaillard WD, Glauser T, Goldstein JL, Goodkin HP, Guerriero RM, Lai YC, McDonough TL, Mikati MA, Morgan LA, Novotny EJ, Ostendorf AP, Payne ET, Peariso K, Piantino J, Riviello JJ, Sands TT, Sannagowdara K, Tasker RC, Tchapyjnikov D, Topjian A, Wainwright MS, Wilfong A, Williams K, Loddenkemper T

Pediatr Crit Care Med (2021) · DOI → · PubMed

Status EpilepticusPharmacologyOutcomes

Factors associated with long-term outcomes in pediatric refractory status epilepticus

Gaínza-Lein M, Barcia Aguilar C, Piantino J, Chapman KE, Sánchez Fernández I, Amengual-Gual M, Anderson A, Appavu B, Arya R, Brenton JN, Carpenter JL, Clark J, Farias-Moeller R, Gaillard WD, Glauser TA, Goldstein JL, Goodkin HP, Huh L, Kahoud R, Kapur K, Lai YC, McDonough TL, Mikati MA, Morgan LA, Nayak A, Novotny E, Ostendorf AP, Payne ET, Peariso K, Reece L, Riviello J, Sannagowdara K, Sands TT, Sheehan T, Tasker RC, Tchapyjnikov D, Vasquez A, Wainwright MS, Wilfong A, Williams K, Zhang B, Loddenkemper T

Epilepsia (2021) · DOI → · PubMed

Status EpilepticusBiomarkersOutcomes

Benzodiazepine administration patterns before escalation to second-line medications in pediatric refractory convulsive status epilepticus

Sheehan T, Amengual-Gual M, Vasquez A, Abend NS, Anderson A, Appavu B, Arya R, Barcia Aguilar C, Brenton JN, Carpenter JL, Chapman KE, Clark J, Farias-Moeller R, Gaillard WD, Gaínza-Lein M, Glauser TA, Goldstein JL, Goodkin HP, Guerriero RM, Huh L, Jackson M, Kapur K, Kahoud R, Lai YC, McDonough TL, Mikati MA, Morgan LA, Novotny EJ, Ostendorf AP, Payne ET, Peariso K, Piantino J, Reece L, Riviello JJ, Sands TT, Sannagowdara K, Shellhaas R, Smith G, Tasker RC, Tchapyjnikov D, Topjian AA, Wainwright MS, Wilfong A, Williams K, Zhang B, Loddenkemper T

Epilepsia (2021) · DOI → · PubMed

Status EpilepticusPharmacologyOutcomes

Early Clinical Variables Associated With Refractory Convulsive Status Epilepticus in Children

Peariso K, Arya R, Glauser T, Abend NS, Barcia Aguilar C, Amengual-Gual M, Anderson A, Appavu BL, Brenton JN, Carpenter J, Chapman KE, Clark J, Gaillard WD, Gaínza-Lein M, Goldstein J, Goodkin H, Grinspan Z, Guerriero RM, Horn PS, Huh L, Kahoud R, Kelley SA, Kossoff EH, Kapur K, Lai YC, Marquis BO, McDonough T, Mikati MA, Morgan L, Novotny E, Ostendorf AP, Payne ET, Piantino J, Riviello J, Sands T, Stafstrom CE, Tasker RC, Tchapyjnikov D, Vasquez A, Wainwright MS, Wilfong A, Williams K, Loddenkemper T

Neurology (2023) · DOI → · PubMed

Status EpilepticusPharmacologyBiomarkers

Pediatric status epilepticus management by Emergency Medical Services (the pSERG cohort)

Amengual-Gual M, Sánchez Fernández I, Vasquez A, Abend NS, Anderson A, Arya R, Barcia Aguilar C, Brenton JN, Carpenter JL, Chapman KE, Clark J, Farias-Moeller R, Gaillard WD, Glauser TA, Goldstein JL, Goodkin HP, Lai YC, Mikati MA, Morgan LA, Novotny EJ, Ostendorf AP, Payne ET, Peariso K, Piantino J, Reece L, Riviello JJ, Sannagowdara K, Sheehan T, Tasker RC, Tchapyjnikov D, Topjian AA, Wainwright MS, Wilfong A, Williams K, Loddenkemper T

Seizure (2023) · DOI → · PubMed

Status EpilepticusPharmacologyOutcomes

Time to treatment in pediatric patients with repeated episodes of status epilepticus

Gettings JV, Fernández IS, Anderson A, Brenton JN, Can A, Clark J, Moeller RF, Goodkin HP, Lai YC, Mikati MA, Morgan LA, Novotny E, Ostendorf AP, Piantino J, Riviello JJ, Sannagowdara K, Tasker RC, Tchapyjnikov D, Wainwright MS, Wilfong A, Williams K, Zhang B, Loddenkemper T, Gaínza-Lein M

BMC Neurol (2025) · DOI → · PubMed

Status EpilepticusEducationPharmacologyBiomarkers

Epilepsy and proxy-reported health-related quality of life in children and young people with non-ambulatory cerebral palsy.

Ostendorf AP, Axeen ET, Eschbach K, Fedak Romanowski E, Morgan LA, Gross P, Narayanan UG, Glader L, Noritz G

Dev Med Child Neurol (2022) · DOI → · PubMed

SeizuresEpilepsyPharmacology

Prioritizing Hormone Therapy Over Vigabatrin as the First Treatment for Infantile Spasms: A Quality Improvement Initiative.

Mytinger JR, Parker W, Rust SW, Ahrens SM, Albert DVF, Beatty CW, Chrisman J, Clark DJ, Debs A, Denney D, Karn M, Herbst J, Ostendorf AP, Taylor MC, Twanow JDE, Vidaurre J, Patel AD

Neurology (2022) · DOI → · PubMed

SeizuresOutcomes

Epilepsy center characteristics and geographic region influence presurgical testing in the United States.

Ahrens SM, Arredondo KH, Bagić AI, Bai S, Chapman KE, Ciliberto MA, Clarke DF, Eisner M, Fountain NB, Gavvala JR, Perry MS, Rossi KC, Wong-Kisiel LC, Herman ST, Ostendorf AP

Epilepsia (2022) · DOI → · PubMed

EpilepsyOutcomesPharmacology

Association Between Characteristics of National Association of Epilepsy Centers and Reported Utilization of Specific Surgical Techniques.

Arredondo KH, Ahrens SM, Bagić AI, Bai S, Chapman KE, Ciliberto MA, Clarke DF, Eisner M, Fountain NB, Gavvala JR, Perry MS, Rossi KC, Wong-Kisiel LC, Herman ST, Ostendorf AP

Neurology (2022) · DOI → · PubMed

SeizuresEpilepsyPharmacology

Molecular and spatial heterogeneity of microglia in Rasmussen encephalitis.

Westfall JJ, Schwind WN, Sran S, Navarro JB, Leonard J, Pindrik JA, Pierson CR, Boué DR, Koboldt DC, Ostendorf AP, Wilson RK, Mardis ER, Miller KE, Bedrosian TA

Acta Neuropathol Commun (2022) · DOI → · PubMed

EpilepsyPharmacologyAutoimmune

Associations between testing and treatment pathways in lesional temporal or extratemporal epilepsy: A census survey of NAEC center directors.

Beatty CW, Ahrens SM, Arredondo KH, Bagić AI, Bai S, Chapman KE, Ciliberto MA, Clarke DF, Eisner M, Fountain NB, Gavvala JR, Perry MS, Rossi KC, Wong-Kisiel LC, Herman ST, Ostendorf AP

Epilepsia (2023) · DOI → · PubMed

EEGEpilepsyNeuroimagingPharmacology

Post-ictal Rhythmic Thalamic Activity of the Centromedian Nucleus.

Arredondo K, Ostendorf AP, Ahrens S, Beatty CW, Pindrik J, Shaikhouni A

J Clin Neurophysiol (2023) · DOI → · PubMed

EEGSeizuresEpilepsyPharmacology

Impact of Etiology on Seizure and Quantitative Functional Outcomes in Children with Cerebral Palsy and Medically Intractable Epilepsy Undergoing Hemispherotomy/Hemispherectomy.

Damante MA, Rosenberg N, Shaikhouni A, Johnson HK, Leonard JW, Ostendorf AP, Pindrik JA

World Neurosurg (2023) · DOI → · PubMed

SeizuresEpilepsyOutcomes

Epilepsy Impacts Families and Communities: Persistent Gaps and Inequities.

Ostendorf AP

Semin Pediatr Neurol (2023) · DOI → · PubMed

SeizuresEpilepsyEducationSleep

A multi-center comparison of surgical techniques for corpus Callosotomy in pediatric drug-resistant epilepsy.

Hansen D, Shandley S, Olaya J, Hauptman J, Auguste K, Ostendorf AP, Depositario-Cabacar DF, Wong-Kisiel LC, Reddy SB, McCormack MJ, Gonzalez-Giraldo E, Sullivan J, Pradeep J, Singh RK, Romanowski EF, McNamara NA, Ciliberto MA, Tatachar P, Shrey DW, Karakas C, Karia S, Kheder A, Gedela S, Alexander A, Eschbach K, Bolton J, Marashly A, Wolf S, McGoldrick P, Nangia S, Grinspan Z, Coryell J, Samanta D, Armstrong D, Perry MS

Epilepsia (2023) · DOI → · PubMed

SeizuresEpilepsyOutcomesPharmacology

Epilepsy monitoring unit practices and safety among NAEC epilepsy centers: A census survey.

Bagić AI, Ahrens SM, Chapman KE, Bai S, Clarke DF, Eisner M, Fountain NB, Gavvala JR, Rossi KC, Herman ST, Ostendorf AP

Epilepsy Behav (2023) · DOI → · PubMed

Cardiac ArrestEEGSeizuresEpilepsyStatus EpilepticusOutcomes

Epilepsy surgery in children with genetic etiologies: A prospective evaluation of current practices and outcomes.

Coryell J, Singh R, Ostendorf AP, Eisner M, Alexander A, Eschbach K, Shrey DW, Olaya J, Ciliberto MA, Karakas C, Karia S, McNamara N, Romanowski EF, Kheder A, Pradeep J, Reddy SB, McCormack MJ, Bolton J, Wolf S, McGoldrick P, Hauptman JS, Samanta D, Tatachar P, Sullivan J, Auguste K, Gonzalez-Giraldo E, Marashly A, Depositario-Cabacar DF, Wong-Kisiel LC, Perry S

Seizure (2023) · DOI → · PubMed

EEGSeizuresEpilepsyNeuroimagingOutcomesPharmacology

Pediatric neuromodulation for drug-resistant epilepsy: Survey of current practices, techniques, and outcomes across US epilepsy centers.

Joshi CN, Karakas C, Eschbach K, Samanta D, Auguste K, Desai V, Singh R, McGoldrick P, Wolf S, Abel TJ, Novotny E, Oluigbo C, Reddy SB, Alexander A, Price A, Reeders P, Mcnamara N, Romanowski EF, Mutchnick I, Ostendorf AP, Shaikhouni A, Knox A, Aungaroon G, Olaya J, Muh CR

Epilepsia Open (2024) · DOI → · PubMed

SeizuresEpilepsyOutcomesPharmacology

Determinants of successful ictal SPECT injection in phase 1 epilepsy presurgical evaluation: Findings from the pediatric epilepsy research consortium surgery database project.

Joshi C, Singh R, Liu G, Karakas C, Ciliberto M, Eschbach K, Perry MS, Shrey D, Morphew T, Ostendorf AP, Reddy SB, McCormack MJ, Karia S, Nangia S, Wong-Kisiel L

Epilepsia Open (2024) · DOI → · PubMed

EEGSeizuresEpilepsyOutcomesPharmacology

Pediatric Palliative Epilepsy Surgery: A Report From the Pediatric Epilepsy Research Consortium (PERC) Surgery Database.

Jeno M, Zimmerman MB, Shandley S, Wong-Kisiel L, Singh RK, McNamara N, Fedak Romanowski E, Grinspan ZM, Eschbach K, Alexander A, McGoldrick P, Wolf S, Nangia S, Bolton J, Olaya J, Shrey DW, Karia S, Karakas C, Tatachar P, Ostendorf AP, Gedela S, Javarayee P, Reddy S, Manuel CM, Gonzalez-Giraldo E, Sullivan J, Coryell J, Depositario-Cabacar DFT, Hauptman JS, Samanta D, Armstrong D, Perry MS, Marashly A, Ciliberto M

Pediatr Neurol (2024) · DOI → · PubMed

EEGSeizuresEpilepsyOutcomesPharmacology

Status Epilepticus Protocol Variation Across Accredited National Association of Epilepsy Centers Members.

Lamberta LK, Asmar M, Fredwall MM, Ahrens SM, Bai S, Eisner M, Lado FA, Schuele SU, Clarke DF, Abdelmoity AT, Davis KA, Hopp JL, Koubeissi MZ, Bensalem Owen MK, Herman ST, Ostendorf AP

Neurology (2025) · DOI → · PubMed

EpilepsyStatus Epilepticus

The Impact of Social Determinants of Health on Quality of Life in a Cohort of 1300 Children With Epilepsy.

Beatty CW, Ahrens SM, Arredondo KH, Twanow JD, Shaikhouni A, Eisner M, Auer N, Bhatnagar S, Ostendorf AP

Pediatr Neurol (2025) · DOI → · PubMed

SeizuresEpilepsyOutcomesPharmacologySleep

Factors Associated With More Medication Trials Before Surgical Evaluation and Postsurgical Outcomes in Pediatric Drug-Resistant Epilepsy.

Samanta D, Newell G, Caraway AR, Brock E, Albert GW, Novotny EJ, Depositario Cabacar DF, Oluigbo CO, Gaillard WD, Tatachar P, Bolton JB, Wong-Kisiel L, Romanowski EF, Mcnamara NA, Eschbach K, Alexander AL, Auguste KI, Gonzalez-Giraldo E, Bernardo D, Ostendorf AP, Coryell J, Karia S, Karakas C, Javarayee PK, Pichon PD, Olaya J, Shrey DW, Reddy SB, Ganesh A, Hauptman JS, Singh RK, Ciliberto M, Marashly A, Grinspan ZM, Nangia S, Arredondo K, Miller DJ, Sattar S, Montenegro M, Agarwal N, Galan FN, Wagner J, Abel TJ, Knox AT, Perry MS

Neurology (2025) · DOI → · PubMed

SeizuresEpilepsyNeuroimagingOutcomesPharmacology

Outcomes of Early-Life Focal Cortical Dysplasia-Related Epilepsy: A PERC Surgery Study.

Cohen NT, Depositario-Cabacar DF, Oluigbo CO, Ostendorf AP, Wong-Kisiel L, Fedak Romanowski E, McNamara NA, Tatachar P, Eschbach K, Alexander AL, Pichon PD, Ciliberto MA, Gonzalez-Giraldo E, Bernardo D, Auguste KI, Coryell J, Arredondo KH, Novotny EJ, Reddy SB, Ganesh A, Marashly A, Javarayee PK, Singh RK, Bolton JB, Grinspan ZM, Karia S, Karakas C, Lin J, Knox AT, Wolf SM, Abel TJ, Samanta D, Armstrong DM, Pavuluri S, Hyslop A, Galan FN, Miller DJ, Hauptman JS, Caraway AR, Perry MS, Gaillard WD

Neurol Clin Pract (2025) · DOI → · PubMed

SeizuresEpilepsyOutcomesPharmacology

Associations Between Testing and Treatment Pathways in a Case of Pediatric Nonlesional Epilepsy: A Census Survey of NAEC Center Directors.

Beatty CW, Ahrens SM, Arredondo KH, Bagic AI, Bai S, Chapman KE, Ciliberto MA, Clarke DF, Eisner M, Fountain NB, Gavvala JR, Perry MS, Rossi KC, Wong-Kisiel LC, Herman ST, Ostendorf AP

J Child Neurol (2024) · DOI → · PubMed

EpilepsyPharmacology

Expert opinion on use of vagus nerve stimulation therapy in the management of pediatric epilepsy: A Delphi consensus study.

Wheless JW, Raskin JS, Fine AL, Knupp KG, Schreiber J, Ostendorf AP, Albert GW, Kossoff EH, Madsen JR, Kotagal P, Numis AL, Gadgil N, Holder DL, Thiele EA, Ibrahim GM

Seizure (2024) · DOI → · PubMed

Epilepsy

Associations between Electroencephalographic Variables, Early Post-Traumatic Seizure Risk, and Outcomes following Pediatric Severe Traumatic Brain Injury.

Nickerson TE, Villo L, Eisner M, Lovett ME, Chung MG, O'Brien NF, Sribnick EA, Ostendorf AP

J Pediatr Intensive Care (2022) · DOI → · PubMed

EEGSeizuresTBIOutcomes

Disparities across the pediatric epilepsy surgery journey: Referral, recommendation, and completion from a national consortium.

Berl MM, Wagner J, Caraway A, Loblein H, Novotny EJ, Patrick K, Ostendorf AP, Alexander AL, Eschbach KL, Depositario-Cabacar DF, Vu TA, Oluigbo C, Karia SR, Karakas C, Wong-Kisiel LC, Romanowski EF, McNamara NA, Bolton J, Ailion A, Tatachar P, Pichon PD, Shrey DW, Singh RK, Coryell J, Lin JJ, Koop J, Gonzalez-Giraldo E, Auguste K, Bernardo D, Ciliberto MA, Reddy SB, Ganesh A, Arredondo K, Grinspan Z, Nangia S, Samanta D, Marashly A, Armstrong D, Perry MS

Epilepsia (2026) · DOI → · PubMed

Epilepsy

Corpus Callosotomy or Focal Surgery in Children Presenting With Generalized Tonic Seizures: Findings From the Pediatric Epilepsy Research Consortium.

Karakas C, Warren AEL, Knowles JK, Perry MS, Caraway A, Wong-Kisiel L, Javarayee P, Olaya J, Shrey D, Karia S, Sah J, Ostendorf AP, Tatachar P, Alexander AL, Eschbach K, Bolton J, Reddy SB, McCormack MJ, Singh R, Depositario-Cabacar D, Ciliberto M, Coryell J, Romanowski EF, McNamara N, Giraldo EG, Auguste K, Singhal NS, Clarke DF

Pediatr Neurol (2026) · DOI → · PubMed

SeizuresEpilepsyOutcomes